U.S. stock higher in pre-market trading for,Sept 15.The Dow Futures is trading at 28,051.00 up with +0.65% percent or +180.00 point.The S&P 500 Futures is trading at 3,395.62 up with +0.69%percent or +23.42 point.The Nasdaq Futures is trading at 11,373.40 up with +0.95% percent or +106.88 point.

In other parts of world, Japan’s Nikkei 225 is trading at at 23,454.89 with a loss of – percent or –104.41 point. Hong Kong’s Hang Seng is trading at 24,740.62 up with + percent or   +100.34 point. China’s Shanghai  Composite is trading at 3,295.68 up with + percent or +16.87 point. India’s BSE Sensex is trading at 38,876.86 up with + percent or  +120.23 point at 12:15 PM.Germany’s DAX is trading at 13,241.21 up with + percent or  +47.55 point. France’s CAC 40 is trading at 5,076.22 up with + percent or  +24.34 point. The Stoxx Europe 600 is trading at 371.33 up with + percent or   +2.82 point.

Tuesday’s Factors and Events

the chief executives of nine major drugmakers pledged not to seek approval for their vaccines until their safety and effectiveness was proven in large clinical trials. The letter came amid reports that Trump was attempting to bypass the FDA’s approvals process or get fast-track emergency use approval for an experimental vaccine, even if it hasn’t yet received full regulatory approval. CNBC has reached out to the White House for comment.

“In the interest of public health, we pledge to always make the safety and well-being of vaccinated individuals our top priority,” the letter said. It was signed by the CEOs of Pfizer, AstraZeneca, BioNTech, GlaxoSmithKline, Johnson & Johnson, Merck & Co., Moderna, Novavax and Sanofi.

Monday Activity

For the day the Dow is trading at 27,534.58 with a loss of – percent or 405.89 point. The S&P 500 is trading at 3,339.19 with a loss of – percent or –59.77 point. The Nasdaq Composite is trading at 10,919.59 with a loss of percent or –221.97 point.

Other leading market index closes included the small-cap Russell 2000 Index closed at 1,536.97 up with 2.65% percent or +39.70 point; the S&P 600 Small-Cap Index closed at 877.10 up with + percent or +15.17 point; the S&P 400 Mid-Cap Index closed at 1,891.25 with + percent or +36.38 point; the S&P 100 Index closed at 1,567.06 with  percent or +17.14 point; the Russell 3000 Index closed at 1,977.22  with percent or +30.24 point; the Russell 1000 Index closed at 1,879.69 with +or +27.58 point.

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