U.S. stock futures are lower in pre-market trading for Monday, September 25. The Dow Futures are trading at 22,294.50 with a loss of -0.02% percent or -4.50 point.The S&P 500 Futures are trading at 2,498.38 with a loss of -0.04% percent or -1.12 point.The Nasdaq Futures are trading at 5,927.88 with a loss of -0.13% percent or -8.37 point.

In overnight trading in the Eastern Hemisphere,  Japan’s Nikkei 225 are trading at 20,397.58  for up with +0.50% percent or +101.13 point. Hong Kong’s Hang Seng are trading at 27,500.34  with a loss of –1.36% percent or –380.19 point. China’s Shanghai Composite are trading at 3,341.55  with  a loss of –0.33% percent or  –10.98 point. India’s BSE Sensex are trading at 31,626.63  with  a loss of –0.93% percent or –295.81 point at 12:15 PM. The FTSE 100 are trading at 7,294.94 with a loss of  –0.21% percent or –15.70 point. Germany’s DAX are trading at 12,616.91 for up  with +0.20% percent or +24.56 point. France’s CAC 40 are trading at 5,267.30  with a loss of –0.27% percent or –14.00 point. The Stoxx Europe 600 are trading at 383.86 for up  with +0.17% percent or  +0.69 point.

Monday’s Factors and Events

U.S. stocks closed narrowly mixed Monday as health care stocks recovered most of their losses. The Dow closed out its second consecutive week of gains, up 0.4 percent on the week.

Health care stocks, which were one of the worst performers in the S&P 500 earlier in the day, climbed more than half a percent from session lows to close up 0.08 percent. Top gainers in the health care sector included Medicaid insurer Centene and hospital operators.

The move in biotech and pharmaceutical stocks came after Sen. John McCain, R-Ariz., on Friday said he “cannot in good conscience vote for the Graham Cassidy proposal.

Friday’s Activity

U.S. market were mixed on Friday. For the day the Dow Jones Industrial Average closed at 22,349.59  with a loss of –0.04% percent or –9.64 point. The S&P 500 closed at 2,502.22 for up with +0.06% percent or +1.62 point. The Nasdaq Composite closed at 6,426.92 for up with +0.07% percent or +4.23 point.

Other leading market index closes included the small-cap Russell 2000 Index closed at 1,450.78 for up with  +0.46% percent or +6.60 point; the S&P 600 Small-Cap Index closed at 874.87 for up with +0.68% percent or  +5.91 point; the S&P 400 Mid-Cap Index closed at 1,768.65 for up with  +0.33% percent or +5.82 point; the S&P 100 Index closed at 1,106.61  for up with  +0.02% percent or +0.22 point; the Russell 3000 Index closed at 1,482.86 for up  with +0.11% percent or +1.59 point; the Russell 1000 Index closed at 1,387.33 for up with +0.08% percent or +1.09 point; and the Dow Jones U.S. Select Dividend Index closed at 22,349.59  with a loss of  –0.04% percent or –9.64 point.