U.S. stock futures lower  in pre-market trading for Wednesday, September 05.The Dow Futures is trading at 25,906.00 with a loss of  -0.30% percent or  -79.00 point. The S&P 500 Futures is trading at 2,892.00  with a loss of -0.22% percent or -6.25 point. The Nasdaq Futures is trading at 7,618.75   with a loss of  -0.26% percent or -20.00 point.

In overnight trading in the Eastern Hemisphere,Japan’s Nikkei 225 is trading at 22,580.83 with a loss of -0.51% percent or -116.07 point. Hong Kong’s Hang Seng is trading at 27,267.80  with a loss of  -2.52% percent or  -705.54 point. China’s Shanghai Composite is trading at 2,704.34 with a loss of  -1.68% percent or -46.24  point. India’s BSE Sensex is trading at 37,870.01  with a loss of -0.75% percent or  -287.91 point at 12:15 PM.The FTSE 100 is trading at 7,424.58 with a loss of -0.45% percent or -33.28 point. Germany’s DAX is trading at 12,151.48  with a loss of -0.48% percent or -58.73  point. France’s CAC 40 is trading at 5,299.31  with a loss of -0.81% percent or -43.38 point. The Stoxx Europe 600 is trading at 377.62  with a loss of -0.58% percent or -2.21 point.

Wednesday’s Factors and Events

Trade anxiety continues to worry markets worldwide, as investors await news surrounding the U.S.’ future trading relationship with the likes of Canada and China. The U.S. and Canada failed to secure a new agreement on Friday, to replace the current North American Free Trade Agreement (NAFTA) pact – meaning that extended talks are likely to continue in the coming days, potentially weeks.

Tuesday’s Activity

For the day the Dow is trading at 25,952.48  with a loss of -0.048% percent or -12.34 point. The S&P 500 is trading at 2,896.72   with a loss of -0.17% percent or -4.80 point. The Nasdaq Composite is trading at 8,091.25  with a loss of -0.23% percent or -18.29 point.

Other leading market index closes included the small-cap Russell 2000 Index closed at 1,733.38 with a loss of -0.42% percent or -7.38 point; the S&P 600 Small-Cap Index closed at 1,093.58 with a loss of  -0.44% percent or -4.78 point; the S&P 400 Mid-Cap Index closed at 2,040.46 with a loss of  -0.21% percent or -4.24 point; the S&P 100 Index closed at 1,284.03   with a loss of  -0.22% percent or -2.87 point; the Russell 3000 Index closed at 1,723.24  with a loss of  -0.17% percent or -2.86 point; the Russell 1000 Index closed at 1,608.38   with a loss of -0.14% percent or -2.32  point;